Most takers of mescalin experience only the heavenly part of schizophrenia. The drug brings hell and purgatory only to those who have had a recent case of jaundice, or who suffer from periodical depressions or a chronic anxiety. If, like the other drugs of remotely comparable power, mescalin were notoriously toxic, the taking of it would be enough, of itself, to cause anxiety. But the reasonably healthy person knows in advance that, so far as he is concerned, mescalin is completely innocuous, that its effects will pass off after eight or ten hours, leaving no hangover and consequently no craving for a renewal of the dose. Fortified by this knowledge, he embarks upon the experiment without fear—in other words, without any disposition to convert an unprecedentedly strange and other than human experience into something appalling, something actually diabolical.